Cargando…

Novel idiopathic pulmonary fibrosis susceptibility variants revealed by deep sequencing

BACKGROUND: Specific common and rare single nucleotide variants (SNVs) increase the likelihood of developing sporadic idiopathic pulmonary fibrosis (IPF). We performed target-enriched sequencing on three loci previously identified by a genome-wide association study to gain a deeper understanding of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lorenzo-Salazar, Jose M., Ma, Shwu-Fan, Jou, Jonathan, Hou, Pei-Chi, Guillen-Guio, Beatriz, Allen, Richard J., Jenkins, R. Gisli, Wain, Louise V., Oldham, Justin M., Noth, Imre, Flores, Carlos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Respiratory Society 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556557/ https://www.ncbi.nlm.nih.gov/pubmed/31205927 http://dx.doi.org/10.1183/23120541.00071-2019

Ejemplares similares

Proportion of Idiopathic Pulmonary Fibrosis Risk Explained by Known Common Genetic Loci in European Populations
por: Leavy, Olivia C., et al.
Publicado: (2021)

Shared genetic risk factors: implications for treatment of idiopathic pulmonary fibrosis and systemic hypertension
por: Parcesepe, Gina, et al.
Publicado: (2023)

Genetic overlap between idiopathic pulmonary fibrosis and COVID−19
por: Allen, Richard J, et al.
Publicado: (2022)

Reply to Spek and Duitman
por: Oldham, Justin M., et al.
Publicado: (2023)

The causal relationship between gastro-oesophageal reflux disease and idiopathic pulmonary fibrosis: a bidirectional two-sample Mendelian randomisation study
por: Reynolds, Carl J., et al.
Publicado: (2023)

Leveraging global multi-ancestry meta-analysis in the study of idiopathic pulmonary fibrosis genetics
por: Partanen, Juulia J., et al.
Publicado: (2022)

Cluster analysis of transcriptomic datasets to identify endotypes of idiopathic pulmonary fibrosis
por: Kraven, Luke M, et al.
Publicado: (2023)

PCSK6 and Survival in Idiopathic Pulmonary Fibrosis
por: Oldham, Justin M., et al.
Publicado: (2023)

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study
por: Allen, Richard J, et al.
Publicado: (2017)

Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis
por: Allen, Richard J., et al.
Publicado: (2020)

The Use of Genetic Information to Define Idiopathic Pulmonary Fibrosis in UK Biobank
por: Leavy, Olivia C., et al.
Publicado: (2023)

Mapping brain endophenotypes associated with idiopathic pulmonary fibrosis genetic risk
por: Mohammadi-Nejad, Ali-Reza, et al.
Publicado: (2022)

Telomere length and immunosuppression in non-idiopathic pulmonary fibrosis interstitial lung disease
por: Zhang, David, et al.
Publicado: (2023)

Association study of human leukocyte antigen (HLA) variants and idiopathic pulmonary fibrosis
por: Guillen-Guio, Beatriz, et al.
Publicado: (2023)

A functional genomic model for predicting prognosis in idiopathic pulmonary fibrosis
por: Huang, Yong, et al.
Publicado: (2015)

Central lung gene expression associates with myofibroblast features in idiopathic pulmonary fibrosis
por: Huang, Yong, et al.
Publicado: (2023)

Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity
por: Fadista, João, et al.
Publicado: (2021)

Idiopathic Pulmonary Fibrosis Genetic Risk Factors, Function, and Mechanisms? The Concepts Are Starting to Gel
por: Bonham, Catherine A., et al.
Publicado: (2022)

T cell Co-Stimulatory molecules ICOS and CD28 stratify idiopathic pulmonary fibrosis survival
por: Bonham, Catherine A., et al.
Publicado: (2019)

Beyond epithelial damage: vascular and endothelial contributions to idiopathic pulmonary fibrosis
por: May, James, et al.
Publicado: (2023)

Comorbid Conditions in Idiopathic Pulmonary Fibrosis: Recognition and Management
por: Oldham, Justin M., et al.
Publicado: (2017)

Goldilocks and the Three Trials: Clinical Trials Targeting the α(v)β(6) Integrin in Idiopathic Pulmonary Fibrosis
por: Sime, Patricia, et al.
Publicado: (2022)

On Target: CYFRA 21-1 as an Idiopathic Pulmonary Fibrosis Biomarker
por: Spagnolo, Paolo, et al.
Publicado: (2022)

Genetically increased circulating FUT3 level leads to reduced risk of idiopathic pulmonary fibrosis: a Mendelian randomisation study
por: Nakanishi, Tomoko, et al.
Publicado: (2022)

Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis
por: Dhindsa, Ryan S., et al.
Publicado: (2021)

Time to diagnosis of idiopathic pulmonary fibrosis in the IPF-PRO Registry
por: Snyder, Laurie D, et al.
Publicado: (2020)

Circulating fibrocytes are not disease-specific prognosticators in idiopathic pulmonary fibrosis
por: Stewart, Iain D., et al.
Publicado: (2021)

A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis
por: Coward, William R., et al.
Publicado: (2014)

Home spirometry in patients with idiopathic pulmonary fibrosis: data from the INMARK trial
por: Noth, Imre, et al.
Publicado: (2021)

A systematic review of blood biomarkers with individual participant data meta-analysis of matrix metalloproteinase-7 in idiopathic pulmonary fibrosis
por: Khan, Fasihul A., et al.
Publicado: (2022)

Reply to Lescoat et al. and to Khamis et al.
por: Adegunsoye, Ayodeji, et al.
Publicado: (2019)

Lung function trajectories in patients with idiopathic pulmonary fibrosis
por: Neely, Megan L, et al.
Publicado: (2023)

Three Steps to Cure Pulmonary Fibrosis. Step 1: The Runaway Train or Groundhog Day?
por: Jenkins, R. Gisli
Publicado: (2020)

Monocyte Count as a Prognostic Biomarker in Patients with Idiopathic Pulmonary Fibrosis
por: Kreuter, Michael, et al.
Publicado: (2021)

Antibody-mediated depletion of CCR10(+)EphA3(+) cells ameliorates fibrosis in IPF
por: Hohmann, Miriam S., et al.
Publicado: (2021)

In-hospital mortality trends among patients with idiopathic pulmonary fibrosis in the United States between 2013-2017: a comparison of academic and non-academic programs
por: Alqalyoobi, Shehabaldin, et al.
Publicado: (2020)

Skewed Lung CCR4 to CCR6 CD4(+) T Cell Ratio in Idiopathic Pulmonary Fibrosis Is Associated with Pulmonary Function
por: Adegunsoye, Ayodeji, et al.
Publicado: (2016)

Genome-wide Enrichment of TERT Rare Variants in Idiopathic Pulmonary Fibrosis Patients of Latino Ancestry
por: Zhang, David, et al.
Publicado: (2022)

Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort
por: Organ, Louise A., et al.
Publicado: (2019)

Genomic Insights Into Sepsis Course Using Whole Exome Sequencing
por: Flores, Carlos, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_kgpuo6pjokolgr3mrndk4ojaia