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Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Induces M2 Macrophage Polarization and Inhibits Murine Aortic Aneurysm Formation

BACKGROUND: The pathogenesis of abdominal aortic aneurysm (AAA) is characterized by atherosclerosis with chronic inflammation in the aortic wall. Montelukast is a selective cys-LT 1 receptor antagonist that can suppress atherosclerotic diseases. We evaluated the in vitro properties of montelukast an...

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Detalles Bibliográficos
Autores principales:	Kawai, Yohei, Narita, Yuji, Yamawaki-Ogata, Aika, Usui, Akihiko, Komori, Kimihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556796/ https://www.ncbi.nlm.nih.gov/pubmed/31263710 http://dx.doi.org/10.1155/2019/9104680

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