Value of the Ratio of Monocytes to Lymphocytes for Monitoring Tuberculosis Therapy

OBJECTIVE: The objective of this study was to evaluate the change of the ratio of monocytes to lymphocytes in patients with active tuberculosis, such as to provide reference for clinical diagnosis and treatment. METHODS: All data were collected from the clinical database of The Fifth People's H...

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Autores principales: Wang, Wei, Wang, Li-fei, Liu, Yan-yan, Yang, Fang, Zhu, Lei, Zhang, Xian-hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556807/
https://www.ncbi.nlm.nih.gov/pubmed/31263513
http://dx.doi.org/10.1155/2019/3270393
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author Wang, Wei
Wang, Li-fei
Liu, Yan-yan
Yang, Fang
Zhu, Lei
Zhang, Xian-hui
author_facet Wang, Wei
Wang, Li-fei
Liu, Yan-yan
Yang, Fang
Zhu, Lei
Zhang, Xian-hui
author_sort Wang, Wei
collection PubMed
description OBJECTIVE: The objective of this study was to evaluate the change of the ratio of monocytes to lymphocytes in patients with active tuberculosis, such as to provide reference for clinical diagnosis and treatment. METHODS: All data were collected from the clinical database of The Fifth People's Hospital of Taiyuan, China. A total of 151 patients who had newly diagnosed active tuberculosis with tuberculosis therapy in hospital and 129 healthy controls were selected. RESULTS: Median ratio of monocytes to lymphocytes was 0.45 (IQR: 0.28–0.67) in patients before treatment and 0.32 (IQR: 0.25–0.46) on discharge (P < 0.001). CONCLUSIONS: Ratio of monocytes to lymphocytes may be applied in diagnosis and the chemotherapeutic efficacy of active tuberculosis.
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spelling pubmed-65568072019-07-01 Value of the Ratio of Monocytes to Lymphocytes for Monitoring Tuberculosis Therapy Wang, Wei Wang, Li-fei Liu, Yan-yan Yang, Fang Zhu, Lei Zhang, Xian-hui Can J Infect Dis Med Microbiol Research Article OBJECTIVE: The objective of this study was to evaluate the change of the ratio of monocytes to lymphocytes in patients with active tuberculosis, such as to provide reference for clinical diagnosis and treatment. METHODS: All data were collected from the clinical database of The Fifth People's Hospital of Taiyuan, China. A total of 151 patients who had newly diagnosed active tuberculosis with tuberculosis therapy in hospital and 129 healthy controls were selected. RESULTS: Median ratio of monocytes to lymphocytes was 0.45 (IQR: 0.28–0.67) in patients before treatment and 0.32 (IQR: 0.25–0.46) on discharge (P < 0.001). CONCLUSIONS: Ratio of monocytes to lymphocytes may be applied in diagnosis and the chemotherapeutic efficacy of active tuberculosis. Hindawi 2019-05-27 /pmc/articles/PMC6556807/ /pubmed/31263513 http://dx.doi.org/10.1155/2019/3270393 Text en Copyright © 2019 Wei Wang et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wang, Wei
Wang, Li-fei
Liu, Yan-yan
Yang, Fang
Zhu, Lei
Zhang, Xian-hui
Value of the Ratio of Monocytes to Lymphocytes for Monitoring Tuberculosis Therapy
title Value of the Ratio of Monocytes to Lymphocytes for Monitoring Tuberculosis Therapy
title_full Value of the Ratio of Monocytes to Lymphocytes for Monitoring Tuberculosis Therapy
title_fullStr Value of the Ratio of Monocytes to Lymphocytes for Monitoring Tuberculosis Therapy
title_full_unstemmed Value of the Ratio of Monocytes to Lymphocytes for Monitoring Tuberculosis Therapy
title_short Value of the Ratio of Monocytes to Lymphocytes for Monitoring Tuberculosis Therapy
title_sort value of the ratio of monocytes to lymphocytes for monitoring tuberculosis therapy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556807/
https://www.ncbi.nlm.nih.gov/pubmed/31263513
http://dx.doi.org/10.1155/2019/3270393
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