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Multiomics Analyses of HNF4α Protein Domain Function during Human Pluripotent Stem Cell Differentiation

During mammalian development, liver differentiation is driven by signals that converge on multiple transcription factor networks. The hepatocyte nuclear factor signaling network is known to be essential for hepatocyte specification and maintenance. In this study, we have generated deletion and point...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Tatham, Michael H., Schmidt-Heck, Wolfgang, Swann, Carolyn, Singh-Dolt, Karamjit, Meseguer-Ripolles, Jose, Lucendo-Villarin, Baltasar, Kunath, Tilo, Rudd, Timothy R., Smith, Andrew J.H., Hengstler, Jan G., Godoy, Patricio, Hay, Ronald T., Hay, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556878/
https://www.ncbi.nlm.nih.gov/pubmed/31185456
http://dx.doi.org/10.1016/j.isci.2019.05.028

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