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Stage-specific requirement for Mettl3-dependent m(6)A mRNA methylation during haematopoietic stem cell differentiation

Haematopoietic stem cells (HSCs) maintain balanced self-renewal and differentiation, but how these functions are precisely regulated is not fully understood. N(6)-methyladenosine (m(6)A) mRNA methylation has emerged as an important mode of epitranscriptional gene expression regulation affecting many...

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Detalles Bibliográficos
Autores principales:	Lee, Heather, Bao, Suying, Qian, Yingzhi, Geula, Shay, Leslie, Juliana, Zhang, Chaolin, Hanna, Jacob H., Ding, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556891/ https://www.ncbi.nlm.nih.gov/pubmed/31061465 http://dx.doi.org/10.1038/s41556-019-0318-1

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