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Targeting the SLIT/ROBO pathway in tumor progression: molecular mechanisms and therapeutic perspectives

The SLITs (SLIT1, SLIT2, and SLIT3) are a family of secreted proteins that mediate positional interactions between cells and their environment during development by signaling through ROBO receptors (ROBO1, ROBO2, ROBO3, and ROBO4). The SLIT/ROBO signaling pathway has been shown to participate in axo...

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Detalles Bibliográficos
Autores principales: Jiang, Zhengdong, Liang, Gang, Xiao, Ying, Qin, Tao, Chen, Xin, Wu, Erxi, Ma, Qingyong, Wang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557020/
https://www.ncbi.nlm.nih.gov/pubmed/31217826
http://dx.doi.org/10.1177/1758835919855238