Metagenomics in ophthalmology: current findings and future prospectives

Less than 1% of all microorganisms of the available environmental microbiota can be cultured with the currently available techniques. Metagenomics is a new methodology of high-throughput DNA sequencing, able to provide taxonomic and functional profiles of microbial communities without the necessity...

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Detalles Bibliográficos
Autores principales: Borroni, Davide, Romano, Vito, Kaye, Stephen B, Somerville, Tobi, Napoli, Luca, Fasolo, Adriano, Gallon, Paola, Ponzin, Diego, Esposito, Alfonso, Ferrari, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557081/
https://www.ncbi.nlm.nih.gov/pubmed/31276030
http://dx.doi.org/10.1136/bmjophth-2018-000248
Descripción
Sumario:Less than 1% of all microorganisms of the available environmental microbiota can be cultured with the currently available techniques. Metagenomics is a new methodology of high-throughput DNA sequencing, able to provide taxonomic and functional profiles of microbial communities without the necessity to culture microbes in the laboratory. Metagenomics opens to a ‘hypothesis-free’ approach, giving important details for future research and treatment of ocular diseases in ophthalmology, such as ocular infection and ocular surface diseases.

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