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Development of anti-HER2-targeted doxorubicin–core-shell chitosan nanoparticles for the treatment of human breast cancer

Purpose: Doxorubicin (DOX) encapsulated O-succinyl chitosan graft Pluronic(®) F127 (OCP) copolymer nanoparticles conjugated with an anti-HER2 monoclonal antibody were developed as targeted drug delivery vehicles for the treatment of HER2-overexpressing breast cancer. Methods: Five percent and 10% (w...

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Detalles Bibliográficos
Autores principales:	Naruphontjirakul, Parichart, Viravaidya-Pasuwat, Kwanchanok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557189/ https://www.ncbi.nlm.nih.gov/pubmed/31239670 http://dx.doi.org/10.2147/IJN.S198552

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