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PI3K inhibition enhances the anti-tumor effect of eribulin in triple negative breast cancer
Loss of the tumor suppressor phosphatase and tensin homolog (PTEN) is commonly observed in triple negative breast cancer (TNBC), leading to activation of the phosphoinositide 3-kinase (PI3K) signaling to promote tumor cell growth and chemotherapy resistance. In this study, we investigated whether ad...
Autores principales: | Rajput, Sandeep, Guo, Zhanfang, Li, Shunqiang, Ma, Cynthia X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557212/ https://www.ncbi.nlm.nih.gov/pubmed/31217901 |
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