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1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours
Colorectal cancer (CRC) is the second leading cause of cancer associated deaths in developed countries. Cancer progression and metastatic spread is reliant on new blood vasculature, or angiogenesis. Tumour-related angiogenesis is regulated by pro- and anti-angiogenic factors secreted from malignant...
Autores principales: | Butler, Clare T., Kennedy, Susan A., Buckley, Amy, Doyle, Ronan, Conroy, Emer, Gallagher, William M., O’Sullivan, Jacintha, Kennedy, Breandán N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557215/ https://www.ncbi.nlm.nih.gov/pubmed/31217905 http://dx.doi.org/10.18632/oncotarget.26966 |
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