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Contractile dysfunction and nitrergic dysregulation in small intestine of a primate model of Parkinson’s disease
Bowel dysfunction is a common non-motor symptom in Parkinson’s disease (PD). The main contractile neurotransmitter in the GI tract is acetylcholine (ACh), while nitric oxide (NO) causes the relaxation of smooth muscle in addition to modulating ACh release. The aim of this study was to characterise f...
Autores principales: | Coletto, Erika, Dolan, John S., Pritchard, Sara, Gant, Alex, Hikima, Atsuko, Jackson, Michael J., Benham, Christopher D., Chaudhuri, K. Ray, Rose, Sarah, Jenner, Peter, Iravani, Mahmoud M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557815/ https://www.ncbi.nlm.nih.gov/pubmed/31231674 http://dx.doi.org/10.1038/s41531-019-0081-9 |
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