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Sequence and structural patterns detected in entangled proteins reveal the importance of co-translational folding
Proteins must fold quickly to acquire their biologically functional three-dimensional native structures. Hence, these are mainly stabilized by local contacts, while intricate topologies such as knots are rare. Here, we reveal the existence of specific patterns adopted by protein sequences and struct...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557820/ https://www.ncbi.nlm.nih.gov/pubmed/31182755 http://dx.doi.org/10.1038/s41598-019-44928-3 |