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Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane
Rif1 is involved in telomere homeostasis, DNA replication timing, and DNA double-strand break (DSB) repair pathway choice from yeast to human. The molecular mechanisms that enable Rif1 to fulfill its diverse roles remain to be determined. Here, we demonstrate that Rif1 is S-acylated within its conse...
Autores principales: | Fontana, Gabriele A., Hess, Daniel, Reinert, Julia K., Mattarocci, Stefano, Falquet, Benoît, Klein, Dominique, Shore, David, Thomä, Nicolas H., Rass, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557901/ https://www.ncbi.nlm.nih.gov/pubmed/31182712 http://dx.doi.org/10.1038/s41467-019-10349-z |
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