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BDNF-producing, amyloid β-specific CD4 T cells as targeted drug-delivery vehicles in Alzheimer's disease

BACKGROUND: The delivery of therapeutic proteins to selected sites within the central nervous system (CNS) parenchyma is a major challenge in the treatment of various neurodegenerative disorders. As brain-derived neurotrophic factor (BDNF) is reduced in the brain of people with Alzheimer's dise...

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Detalles Bibliográficos
Autores principales:	Eremenko, Ekaterina, Mittal, Kritika, Berner, Omer, Kamenetsky, Nikita, Nemirovsky, Anna, Elyahu, Yehezqel, Monsonego, Alon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557914/ https://www.ncbi.nlm.nih.gov/pubmed/31085101 http://dx.doi.org/10.1016/j.ebiom.2019.04.019

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