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Clostridium difficile trehalose metabolism variants are common and not associated with adverse patient outcomes when variably present in the same lineage
BACKGROUND: Clostridium difficile ribotype-027, ribotype-078, and ribotype-017 are virulent and epidemic lineages. Trehalose metabolism variants in these ribotypes, combined with increased human trehalose consumption, have been hypothesised to have contributed to their emergence and virulence. METHO...
Autores principales: | Eyre, David W., Didelot, Xavier, Buckley, Anthony M., Freeman, Jane, Moura, Ines B., Crook, Derrick W., Peto, Tim E.A., Walker, A. Sarah, Wilcox, Mark H., Dingle, Kate E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558026/ https://www.ncbi.nlm.nih.gov/pubmed/31036529 http://dx.doi.org/10.1016/j.ebiom.2019.04.038 |
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