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Progesterone decreases gut permeability through upregulating occludin expression in primary human gut tissues and Caco-2 cells
Progesterone plays a protective role in preventing inflammation and preterm delivery during pregnancy. However, the mechanism involved is unknown. Microbial product translocation from a permeable mucosa is demonstrated as a driver of inflammation. To study the mechanism of the protective role of pro...
Autores principales: | Zhou, Zejun, Bian, Chuanxiu, Luo, Zhenwu, Guille, Constance, Ogunrinde, Elizabeth, Wu, Jiapeng, Zhao, Min, Fitting, Sylvia, Kamen, Diane L., Oates, Jim C., Gilkeson, Gary, Jiang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558054/ https://www.ncbi.nlm.nih.gov/pubmed/31182728 http://dx.doi.org/10.1038/s41598-019-44448-0 |
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