Metabolic engineering of Corynebacterium glutamicum S9114 based on whole-genome sequencing for efficient N-acetylglucosamine synthesis

Glucosamine (GlcN) and its acetylated derivative N-acetylglucosamine (GlcNAc) are widely used in the pharmaceutical industries. Here, we attempted to achieve efficient production of GlcNAc via genomic engineering of Corynebacterium glutamicum. Specifically, we ligated the GNA1 gene, which converts G...

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Detalles Bibliográficos
Autores principales: Deng, Chen, Lv, Xueqin, Liu, Yanfeng, Li, Jianghua, Lu, Wei, Du, Guocheng, Liu, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558094/
https://www.ncbi.nlm.nih.gov/pubmed/31198861
http://dx.doi.org/10.1016/j.synbio.2019.05.002

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