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Hepatocellular carcinoma in body builders; an emerging rare but serious complication of androgenic anabolic steroid use

Illicit use of androgenic anabolic steroids (AAS) is a known problem amongst certain groups including body builders and other athletes. Use of these drugs is thought to be high in some areas of South Wales. A number of adverse effects have been associated with use of AAS including the development of...

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Autores principales: Woodward, Christopher, Smith, Josie, Acreman, Dean, Kumar, Nagappan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Hepato-Biliary-Pancreatic Surgery 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558130/
https://www.ncbi.nlm.nih.gov/pubmed/31225420
http://dx.doi.org/10.14701/ahbps.2019.23.2.174
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author Woodward, Christopher
Smith, Josie
Acreman, Dean
Kumar, Nagappan
author_facet Woodward, Christopher
Smith, Josie
Acreman, Dean
Kumar, Nagappan
author_sort Woodward, Christopher
collection PubMed
description Illicit use of androgenic anabolic steroids (AAS) is a known problem amongst certain groups including body builders and other athletes. Use of these drugs is thought to be high in some areas of South Wales. A number of adverse effects have been associated with use of AAS including the development of hepatic adenomas. There have been a handful of rare cases of the development of hepatocellular carcinoma following AAS use. We report two such cases presenting to the same surgical centre in South Wales within six months. We do this with reference to data from Public Health Wales, including the Harm Reduction Wales Needle and Syringe provision report, which indicate a particularly high rate of use of AAS in the surrounding area. We believe these cases are important from the public health point of view. They demonstrate a rare and not widely known about, but potentially fatal adverse effect of AAS, now becoming prevalent with the high use of these drugs. This is important for doctors to be aware of, but also could form the focus of a public health campaign targeted at AAS users.
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spelling pubmed-65581302019-06-20 Hepatocellular carcinoma in body builders; an emerging rare but serious complication of androgenic anabolic steroid use Woodward, Christopher Smith, Josie Acreman, Dean Kumar, Nagappan Ann Hepatobiliary Pancreat Surg Case Report Illicit use of androgenic anabolic steroids (AAS) is a known problem amongst certain groups including body builders and other athletes. Use of these drugs is thought to be high in some areas of South Wales. A number of adverse effects have been associated with use of AAS including the development of hepatic adenomas. There have been a handful of rare cases of the development of hepatocellular carcinoma following AAS use. We report two such cases presenting to the same surgical centre in South Wales within six months. We do this with reference to data from Public Health Wales, including the Harm Reduction Wales Needle and Syringe provision report, which indicate a particularly high rate of use of AAS in the surrounding area. We believe these cases are important from the public health point of view. They demonstrate a rare and not widely known about, but potentially fatal adverse effect of AAS, now becoming prevalent with the high use of these drugs. This is important for doctors to be aware of, but also could form the focus of a public health campaign targeted at AAS users. Korean Association of Hepato-Biliary-Pancreatic Surgery 2019-05 2019-05-31 /pmc/articles/PMC6558130/ /pubmed/31225420 http://dx.doi.org/10.14701/ahbps.2019.23.2.174 Text en Copyright © 2019 by The Korean Association of Hepato-Biliary-Pancreatic Surgery http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Woodward, Christopher
Smith, Josie
Acreman, Dean
Kumar, Nagappan
Hepatocellular carcinoma in body builders; an emerging rare but serious complication of androgenic anabolic steroid use
title Hepatocellular carcinoma in body builders; an emerging rare but serious complication of androgenic anabolic steroid use
title_full Hepatocellular carcinoma in body builders; an emerging rare but serious complication of androgenic anabolic steroid use
title_fullStr Hepatocellular carcinoma in body builders; an emerging rare but serious complication of androgenic anabolic steroid use
title_full_unstemmed Hepatocellular carcinoma in body builders; an emerging rare but serious complication of androgenic anabolic steroid use
title_short Hepatocellular carcinoma in body builders; an emerging rare but serious complication of androgenic anabolic steroid use
title_sort hepatocellular carcinoma in body builders; an emerging rare but serious complication of androgenic anabolic steroid use
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558130/
https://www.ncbi.nlm.nih.gov/pubmed/31225420
http://dx.doi.org/10.14701/ahbps.2019.23.2.174
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AT acremandean hepatocellularcarcinomainbodybuildersanemergingrarebutseriouscomplicationofandrogenicanabolicsteroiduse
AT kumarnagappan hepatocellularcarcinomainbodybuildersanemergingrarebutseriouscomplicationofandrogenicanabolicsteroiduse