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Assessment of Vaccine-Induced Immunity Against Canine Visceral Leishmaniasis

Canine visceral leishmaniasis is an increasingly important public health problem. Dogs infected by Leishmania infantum are the main domestic reservoir of the parasite and play a key role in its transmission to humans. Recent findings have helped in the development of novel diagnostic methods, and of...

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Detalles Bibliográficos
Autor principal: Moreno, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558161/
https://www.ncbi.nlm.nih.gov/pubmed/31214607
http://dx.doi.org/10.3389/fvets.2019.00168
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author Moreno, Javier
author_facet Moreno, Javier
author_sort Moreno, Javier
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description Canine visceral leishmaniasis is an increasingly important public health problem. Dogs infected by Leishmania infantum are the main domestic reservoir of the parasite and play a key role in its transmission to humans. Recent findings have helped in the development of novel diagnostic methods, and of control measures such as vaccines, some of which are already commercially available. However, quantitative procedures should be followed to confirm whether these vaccines elicit a cell-mediated immune response. The present work describes the need for this evaluation, and the techniques available for confirming this type of immune response.
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spelling pubmed-65581612019-06-18 Assessment of Vaccine-Induced Immunity Against Canine Visceral Leishmaniasis Moreno, Javier Front Vet Sci Veterinary Science Canine visceral leishmaniasis is an increasingly important public health problem. Dogs infected by Leishmania infantum are the main domestic reservoir of the parasite and play a key role in its transmission to humans. Recent findings have helped in the development of novel diagnostic methods, and of control measures such as vaccines, some of which are already commercially available. However, quantitative procedures should be followed to confirm whether these vaccines elicit a cell-mediated immune response. The present work describes the need for this evaluation, and the techniques available for confirming this type of immune response. Frontiers Media S.A. 2019-06-04 /pmc/articles/PMC6558161/ /pubmed/31214607 http://dx.doi.org/10.3389/fvets.2019.00168 Text en Copyright © 2019 Moreno. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Moreno, Javier
Assessment of Vaccine-Induced Immunity Against Canine Visceral Leishmaniasis
title Assessment of Vaccine-Induced Immunity Against Canine Visceral Leishmaniasis
title_full Assessment of Vaccine-Induced Immunity Against Canine Visceral Leishmaniasis
title_fullStr Assessment of Vaccine-Induced Immunity Against Canine Visceral Leishmaniasis
title_full_unstemmed Assessment of Vaccine-Induced Immunity Against Canine Visceral Leishmaniasis
title_short Assessment of Vaccine-Induced Immunity Against Canine Visceral Leishmaniasis
title_sort assessment of vaccine-induced immunity against canine visceral leishmaniasis
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558161/
https://www.ncbi.nlm.nih.gov/pubmed/31214607
http://dx.doi.org/10.3389/fvets.2019.00168
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