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Circulating Relaxin-1 Level Is a Surrogate Marker of Myocardial Fibrosis in HFrEF
Introduction: Relaxin-1 (RLN1) has emerged as a possible therapeutic target in myocardial fibrosis due to its anti-fibrotic effects. Previous randomized clinical trials investigated therapeutic role of exogenous relaxin in patients with acute-on-chronic heart failure (HF) and failed to meet clinical...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558211/ https://www.ncbi.nlm.nih.gov/pubmed/31231242 http://dx.doi.org/10.3389/fphys.2019.00690 |