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Two-Week Aflibercept or Erlotinib Administration Does Not Induce Changes in Intestinal Morphology in Male Sprague–Dawley Rats But Aflibercept Affects Serum and Urine Metabolic Profiles
Gastrointestinal toxicity is a frequently observed adverse event during cancer treatment with traditional chemotherapeutics. Currently, traditional chemotherapeutics are often combined with targeted biologic agents. These biologics, however, possess a distinct toxicity profile, and they may also exa...
Autores principales: | Forsgård, Richard A., Marrachelli, Vannina G, Lindén, Jere, Frias, Rafael, Collado, Maria Carmen, Korpela, Riitta, Monleon, Daniel, Spillmann, Thomas, Österlund, Pia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558216/ https://www.ncbi.nlm.nih.gov/pubmed/31176994 http://dx.doi.org/10.1016/j.tranon.2019.04.019 |
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