Potent anti-tumor efficacy of palbociclib in treatment-naïve H3.3K27M-mutant diffuse intrinsic pontine glioma

BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) is a rare and fatal pediatric brain cancer without cure. Seeking therapeutic strategies is still a major challenge in DIPG research. Previous study has shown that dysregulation of G1/S cell cycle checkpoint was common in DIPG and this dysregulation...

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Detalles Bibliográficos
Autores principales: Sun, Yu, Sun, Ye, Yan, Kun, Li, Zhuxuan, Xu, Cheng, Geng, Yibo, Pan, Changcun, Chen, Xin, Zhang, Liwei, Xi, Qiaoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558223/
https://www.ncbi.nlm.nih.gov/pubmed/31060906
http://dx.doi.org/10.1016/j.ebiom.2019.04.043

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