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A Major Role for the Lateral Habenula in Depressive Illness: Physiologic and Molecular Mechanisms
Emerging preclinical and clinical evidence indicate that the lateral habenula plays a major role in the pathophysiology of depressive illness. Aberrant increases in neuronal activity in the lateral habenula, an anti-reward center, signals down-regulation of brainstem dopaminergic and serotonergic fi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558383/ https://www.ncbi.nlm.nih.gov/pubmed/31231247 http://dx.doi.org/10.3389/fpsyt.2019.00320 |