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Transcriptome Analysis of Small Molecule–Mediated Astrocyte-to-Neuron Reprogramming

Chemical reprogramming of astrocytes into neurons represents a promising approach to regenerate new neurons for brain repair, but the underlying mechanisms driving this trans-differentiation process are not well understood. We have recently identified four small molecules – CHIR99021, DAPT, LDN19318...

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Detalles Bibliográficos
Autores principales: Ma, Ning-Xin, Yin, Jiu-Chao, Chen, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558402/
https://www.ncbi.nlm.nih.gov/pubmed/31231645
http://dx.doi.org/10.3389/fcell.2019.00082