p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells

The tumor suppressor p53 has a diverse mutational profile in human malignancies, which is known to influence the potency of various chemotherapeutics, such as platins and anti-metabolites. However, the impact of the mutations in the TP53 gene (coding for p53) on the anti-cancer efficacy of gold comp...

Descripción completa

Detalles Bibliográficos
Autores principales: Dabiri, Yasamin, Abu el Maaty, Mohamed A., Chan, Hoi Yin, Wölker, Jessica, Ott, Ingo, Wölfl, Stefan, Cheng, Xinlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558413/
https://www.ncbi.nlm.nih.gov/pubmed/31231607
http://dx.doi.org/10.3389/fonc.2019.00438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558413/
https://www.ncbi.nlm.nih.gov/pubmed/31231607
http://dx.doi.org/10.3389/fonc.2019.00438

Ejemplares similares