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Systematic evaluation of cancer‐specific genetic risk score for 11 types of cancer in The Cancer Genome Atlas and Electronic Medical Records and Genomics cohorts

BACKGROUND: Genetic risk score (GRS) is an odds ratio (OR)‐weighted and population‐standardized method for measuring cumulative effect of multiple risk‐associated single nucleotide polymorphisms (SNPs). We hypothesize that GRS is a valid tool for risk assessment of most common cancers. METHODS: Util...

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Detalles Bibliográficos
Autores principales:	Shi, Zhuqing, Yu, Hongjie, Wu, Yishuo, Lin, Xiaoling, Bao, Quanwa, Jia, Haifei, Perschon, Chelsea, Duggan, David, Helfand, Brian T., Zheng, Siqun L., Xu, Jianfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Cancer Prevention
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558466/ https://www.ncbi.nlm.nih.gov/pubmed/30968590 http://dx.doi.org/10.1002/cam4.2143

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