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Rational design of novel sirtuin 1 activators via structure-activity insights from application of QSAR modeling

Sirtuin 1 (SIRT1) enzyme regulates major cell activities, and its activation offers lucrative therapeutic potentials for aging diseases including Alzheimer's disease (AD). Regarding the global aging society, continual attention has been given to various chemical scaffolds as a source for the di...

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Detalles Bibliográficos
Autores principales:	Pratiwi, Reny, Prachayasittikul, Veda, Prachayasittikul, Supaluk, Nantasenamat, Chanin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Leibniz Research Centre for Working Environment and Human Factors 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558509/ https://www.ncbi.nlm.nih.gov/pubmed/31217784 http://dx.doi.org/10.17179/excli2019-1274

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