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Medical Diagnostic Tests: A Review of Test Anatomy, Phases, and Statistical Treatment of Data
Diagnostic tests are approaches used in clinical practice to identify with high accuracy the disease of a particular patient and thus to provide early and proper treatment. Reporting high-quality results of diagnostic tests, for both basic and advanced methods, is solely the responsibility of the au...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558629/ https://www.ncbi.nlm.nih.gov/pubmed/31275427 http://dx.doi.org/10.1155/2019/1891569 |
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author | Bolboacă, Sorana D. |
author_facet | Bolboacă, Sorana D. |
author_sort | Bolboacă, Sorana D. |
collection | PubMed |
description | Diagnostic tests are approaches used in clinical practice to identify with high accuracy the disease of a particular patient and thus to provide early and proper treatment. Reporting high-quality results of diagnostic tests, for both basic and advanced methods, is solely the responsibility of the authors. Despite the existence of recommendation and standards regarding the content or format of statistical aspects, the quality of what and how the statistic is reported when a diagnostic test is assessed varied from excellent to very poor. This article briefly reviews the steps in the evaluation of a diagnostic test from the anatomy, to the role in clinical practice, and to the statistical methods used to show their performances. The statistical approaches are linked with the phase, clinical question, and objective and are accompanied by examples. More details are provided for phase I and II studies while the statistical treatment of phase III and IV is just briefly presented. Several free online resources useful in the calculation of some statistics are also given. |
format | Online Article Text |
id | pubmed-6558629 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-65586292019-07-02 Medical Diagnostic Tests: A Review of Test Anatomy, Phases, and Statistical Treatment of Data Bolboacă, Sorana D. Comput Math Methods Med Review Article Diagnostic tests are approaches used in clinical practice to identify with high accuracy the disease of a particular patient and thus to provide early and proper treatment. Reporting high-quality results of diagnostic tests, for both basic and advanced methods, is solely the responsibility of the authors. Despite the existence of recommendation and standards regarding the content or format of statistical aspects, the quality of what and how the statistic is reported when a diagnostic test is assessed varied from excellent to very poor. This article briefly reviews the steps in the evaluation of a diagnostic test from the anatomy, to the role in clinical practice, and to the statistical methods used to show their performances. The statistical approaches are linked with the phase, clinical question, and objective and are accompanied by examples. More details are provided for phase I and II studies while the statistical treatment of phase III and IV is just briefly presented. Several free online resources useful in the calculation of some statistics are also given. Hindawi 2019-05-28 /pmc/articles/PMC6558629/ /pubmed/31275427 http://dx.doi.org/10.1155/2019/1891569 Text en Copyright © 2019 Sorana D. Bolboacă. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Bolboacă, Sorana D. Medical Diagnostic Tests: A Review of Test Anatomy, Phases, and Statistical Treatment of Data |
title | Medical Diagnostic Tests: A Review of Test Anatomy, Phases, and Statistical Treatment of Data |
title_full | Medical Diagnostic Tests: A Review of Test Anatomy, Phases, and Statistical Treatment of Data |
title_fullStr | Medical Diagnostic Tests: A Review of Test Anatomy, Phases, and Statistical Treatment of Data |
title_full_unstemmed | Medical Diagnostic Tests: A Review of Test Anatomy, Phases, and Statistical Treatment of Data |
title_short | Medical Diagnostic Tests: A Review of Test Anatomy, Phases, and Statistical Treatment of Data |
title_sort | medical diagnostic tests: a review of test anatomy, phases, and statistical treatment of data |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558629/ https://www.ncbi.nlm.nih.gov/pubmed/31275427 http://dx.doi.org/10.1155/2019/1891569 |
work_keys_str_mv | AT bolboacasoranad medicaldiagnostictestsareviewoftestanatomyphasesandstatisticaltreatmentofdata |