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Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells

BACKGROUND: Glioma is the most common and lethal type of malignant brain tumor. Accumulating evidence has highlighted that RNA binding protein APOBEC1 complementation factor (A1CF) is involved in various cellular processes by modulating RNA expression, and acts as an oncogene in breast cancer. Howev...

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Detalles Bibliográficos
Autores principales: Song, Yichen, Shao, Lianqi, Xue, Yixue, Ruan, Xuelei, Liu, Xiaobai, Yang, Chunqing, Zheng, Jian, Shen, Shuyuan, Chen, Jiajia, Li, Zhen, Liu, Yunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558706/
https://www.ncbi.nlm.nih.gov/pubmed/31186064
http://dx.doi.org/10.1186/s13046-019-1200-5