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Does VEGF-targeted active immunotherapy induce complete abrogation of platelet VEGF levels?
OBJECTIVES: Vascular endothelial growth factor (VEGF) is involved in physiological angiogenesis, but also is considered one of the key factors that promotes tumor angiogenesis. CIGB-247 is a VEGF-based vaccine that has been evaluated in phase I clinical trial patients with advanced solid tumors. Thi...
Autores principales: | Sánchez Ramírez, Javier, Bequet-Romero, Mónica, Morera Díaz, Yanelys, Hernández-Bernal, Francisco, Ayala Avila, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558718/ https://www.ncbi.nlm.nih.gov/pubmed/31182141 http://dx.doi.org/10.1186/s13104-019-4368-z |
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