Apolipoprotein E4, inhibitory network dysfunction, and Alzheimer’s disease

Apolipoprotein (apo) E4 is the major genetic risk factor for Alzheimer’s disease (AD), increasing risk and decreasing age of disease onset. Many studies have demonstrated the detrimental effects of apoE4 in varying cellular contexts. However, the underlying mechanisms explaining how apoE4 leads to c...

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Detalles Bibliográficos
Autores principales: Najm, Ramsey, Jones, Emily A., Huang, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558779/
https://www.ncbi.nlm.nih.gov/pubmed/31186040
http://dx.doi.org/10.1186/s13024-019-0324-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558779/
https://www.ncbi.nlm.nih.gov/pubmed/31186040
http://dx.doi.org/10.1186/s13024-019-0324-6

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