Cargando…
Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
BACKGROUND: Prostate cancer (PCa) is considered one of the most prevalent malignancy globally, and metastasis is a major cause of death. Apigenin (API) is a dietary flavonoid which exerts an antimetastatic effect in various cancer types. Sparc/osteonectin, cwcv, and kazal-like domains proteoglycan 1...
Autores principales: | Chien, Ming-Hsien, Lin, Yung-Wei, Wen, Yu-Ching, Yang, Yi-Chieh, Hsiao, Michael, Chang, Junn-Liang, Huang, Hsiang-Ching, Lee, Wei-Jiunn |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558790/ https://www.ncbi.nlm.nih.gov/pubmed/31182131 http://dx.doi.org/10.1186/s13046-019-1247-3 |
Ejemplares similares
-
Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition
por: Lin, Yung-Wei, et al.
Publicado: (2023) -
Downregulating CD26/DPPIV by apigenin modulates the interplay between Akt and Snail/Slug signaling to restrain metastasis of lung cancer with multiple EGFR statuses
por: Chang, Jer-Hwa, et al.
Publicado: (2018) -
SPOCK1 promotes the invasion and metastasis of gastric cancer through Slug‐induced epithelial‐mesenchymal transition
por: Chen, Dehu, et al.
Publicado: (2017) -
Elf5 inhibits epithelial mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2/Slug
por: Chakrabarti, Rumela, et al.
Publicado: (2012) -
Apigenin inhibits NF-κB and Snail signaling, EMT and metastasis in human hepatocellular carcinoma
por: Qin, Yuan, et al.
Publicado: (2016)