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High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer

BACKGROUND: α3β1 integrin is a promising cancer biomarker and drug target. We previously identified a 9-amino-acid cyclic peptide LXY30 for detecting α3β1 integrin on the surface of live tumor cells. This study was undertaken to characterize LXY30 in the detection, cellular function, imaging, and ta...

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Detalles Bibliográficos
Autores principales: Xiao, Wenwu, Ma, Weijie, Wei, Sixi, Li, Qianping, Liu, Ruiwu, Carney, Randy P., Yang, Kevin, Lee, Joyce, Nyugen, Alan, Yoneda, Ken Y., Lam, Kit S., Li, Tianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558829/
https://www.ncbi.nlm.nih.gov/pubmed/31182116
http://dx.doi.org/10.1186/s13045-019-0740-7