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High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer
BACKGROUND: α3β1 integrin is a promising cancer biomarker and drug target. We previously identified a 9-amino-acid cyclic peptide LXY30 for detecting α3β1 integrin on the surface of live tumor cells. This study was undertaken to characterize LXY30 in the detection, cellular function, imaging, and ta...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558829/ https://www.ncbi.nlm.nih.gov/pubmed/31182116 http://dx.doi.org/10.1186/s13045-019-0740-7 |