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α-synuclein in the pathophysiology of Alzheimer’s disease

The Alzheimer’s disease (AD) afflicted brain is neuropathologically defined by extracellular amyloid-β (Aβ) plaques and intraneuronal neurofibrillary tangles composed of hyperphosphorylated tau protein. However, accumulating evidence suggests that the presynaptic protein α-synuclein (αSyn), mainly a...

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Detalles Bibliográficos
Autores principales: Twohig, Daniel, Nielsen, Henrietta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558879/
https://www.ncbi.nlm.nih.gov/pubmed/31186026
http://dx.doi.org/10.1186/s13024-019-0320-x