Dynamic genome-scale cell-specific metabolic models reveal novel inter-cellular and intra-cellular metabolic communications during ovarian follicle development

BACKGROUND: The maturation of the female germ cell, the oocyte, requires the synthesis and storing of all the necessary metabolites to support multiple divisions after fertilization. Oocyte maturation is only possible in the presence of surrounding, diverse, and changing layers of somatic cells. Our...

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Detalles Bibliográficos
Autores principales: Peñalver Bernabé, Beatriz, Thiele, Ines, Galdones, Eugene, Siletz, Anaar, Chandrasekaran, Sriram, Woodruff, Teresa K., Broadbelt, Linda J., Shea, Lonnie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558917/
https://www.ncbi.nlm.nih.gov/pubmed/31182013
http://dx.doi.org/10.1186/s12859-019-2825-2

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