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Gambogic Acid Shows Anti-Proliferative Effects on Non-Small Cell Lung Cancer (NSCLC) Cells by Activating Reactive Oxygen Species (ROS)-Induced Endoplasmic Reticulum (ER) Stress-Mediated Apoptosis

BACKGROUND: Gambogic acid (AG) is believed to be a potent anti-cancer agent. ER (endoplasmic reticulum) stress-induced cell apoptosis was identified as one of the anti-proliferative mechanisms of several anti-cancer agents. In this study, we investigated the involvement of ER stress-induced apoptosi...

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Detalles Bibliográficos
Autores principales: Zhu, Minghua, Jiang, Yinfang, Wu, Hao, Shi, Wei, Lu, Guirong, Cong, Degang, Liu, Keyuan, Song, Shaohui, Ren, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559008/
https://www.ncbi.nlm.nih.gov/pubmed/31138775
http://dx.doi.org/10.12659/MSM.916835