The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders

The neuroimmune system plays a crucial role in the regulation of mood disorders. Moreover, recent studies show that brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is a key regulator in the neuroimmune axis. However, the potential mechanism of BDNF action in the neuroi...

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Detalles Bibliográficos
Autores principales: Jin, Yang, Sun, Li Hua, Yang, Wei, Cui, Ran Ji, Xu, Song Bai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559010/
https://www.ncbi.nlm.nih.gov/pubmed/31231295
http://dx.doi.org/10.3389/fneur.2019.00515
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author Jin, Yang
Sun, Li Hua
Yang, Wei
Cui, Ran Ji
Xu, Song Bai
author_facet Jin, Yang
Sun, Li Hua
Yang, Wei
Cui, Ran Ji
Xu, Song Bai
author_sort Jin, Yang
collection PubMed
description The neuroimmune system plays a crucial role in the regulation of mood disorders. Moreover, recent studies show that brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is a key regulator in the neuroimmune axis. However, the potential mechanism of BDNF action in the neuroimmune axis' regulation of mood disorders remains unclear. Therefore, in this review, we focus on the recent progress of BDNF in influencing mood disorders, by participating in alterations of the neuroimmune axis. This may provide evidence for future studies in this field.
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spelling pubmed-65590102019-06-21 The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders Jin, Yang Sun, Li Hua Yang, Wei Cui, Ran Ji Xu, Song Bai Front Neurol Neurology The neuroimmune system plays a crucial role in the regulation of mood disorders. Moreover, recent studies show that brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is a key regulator in the neuroimmune axis. However, the potential mechanism of BDNF action in the neuroimmune axis' regulation of mood disorders remains unclear. Therefore, in this review, we focus on the recent progress of BDNF in influencing mood disorders, by participating in alterations of the neuroimmune axis. This may provide evidence for future studies in this field. Frontiers Media S.A. 2019-06-04 /pmc/articles/PMC6559010/ /pubmed/31231295 http://dx.doi.org/10.3389/fneur.2019.00515 Text en Copyright © 2019 Jin, Sun, Yang, Cui and Xu. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Jin, Yang
Sun, Li Hua
Yang, Wei
Cui, Ran Ji
Xu, Song Bai
The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders
title The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders
title_full The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders
title_fullStr The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders
title_full_unstemmed The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders
title_short The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders
title_sort role of bdnf in the neuroimmune axis regulation of mood disorders
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559010/
https://www.ncbi.nlm.nih.gov/pubmed/31231295
http://dx.doi.org/10.3389/fneur.2019.00515
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