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Variation in body mass index in patients with chronic obstructive pulmonary disease

INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is associated with systemic inflammation. Weight loss seen in patients with COPD is a consequence of this inflammation. We hypothesized that higher grades of COPD are associated with greater degree of weight loss. MATERIALS AND METHODS: In t...

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Detalles Bibliográficos
Autores principales: Paudel, Mukesh S., Mandal, Amrendra, Kafle, Paritosh, Sidhu, Jasdeep S., Puri, Pradeep, Chaulagai, Baikuntha, Mojahedi, Azad, Gayam, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559103/
https://www.ncbi.nlm.nih.gov/pubmed/31198716
http://dx.doi.org/10.4103/jfmpc.jfmpc_158_19
Descripción
Sumario:INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is associated with systemic inflammation. Weight loss seen in patients with COPD is a consequence of this inflammation. We hypothesized that higher grades of COPD are associated with greater degree of weight loss. MATERIALS AND METHODS: In this cross-sectional study, we assessed the body mass index (BMI) of 34 patients with COPD proven by handheld spirometer. The difference in BMI among various grades of COPD was compared. RESULTS: BMI was found to be inversely related to the grades of COPD in our study (P = 0.001). No significant difference was seen among the patients with regards to age and duration of symptoms before presentation. CONCLUSION: Advanced COPD is associated with greater degree of weight loss.