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Kinetic model for adherent Vero cell growth and poliovirus production in batch bioreactors
The production of poliovirus vaccines in adherent Vero cells in batch bioreactors usually consists of a two-step upstream process: (1) Vero cell cultivation on microcarriers and (2) poliovirus proliferation. In this study we developed a mathematical model to describe this two-step process. We introd...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Applied Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559155/ https://www.ncbi.nlm.nih.gov/pubmed/31217725 http://dx.doi.org/10.1016/j.procbio.2019.03.010 |