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Comparison of osteogenic differentiation induced by siNoggin and pBMP-2 delivered by lipopolysaccharide-amine nanopolymersomes and underlying molecular mechanisms

Purpose: Gene therapies via Noggin small interfering (si)RNA (siNoggin) and bone morphogenetic protein (BMP)-2 plasmid DNA (pBMP-2) may be promising strategies for bone repair/regeneration, but their ideal delivery vectors, efficacy difference, and underlying mechanisms have not been explored, so th...

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Detalles Bibliográficos
Autores principales:	Huang, Mingdi, Zhang, Xinchun, Li, Jing, Li, Yanshan, Wang, Qinmei, Teng, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559258/ https://www.ncbi.nlm.nih.gov/pubmed/31239677 http://dx.doi.org/10.2147/IJN.S203540

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