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Computational modeling of retinal hypoxia and photoreceptor degeneration in patients with age-related macular degeneration
Although drusen have long been acknowledged as a primary hallmark of dry age-related macular degeneration (AMD) their role in the disease remains unclear. We hypothesize that drusen accumulation increases the barrier to metabolite transport ultimately resulting in photoreceptor cell death. To invest...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559637/ https://www.ncbi.nlm.nih.gov/pubmed/31185022 http://dx.doi.org/10.1371/journal.pone.0216215 |