A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data

Analysis methods based on simulations and optimization have been previously developed to estimate relative translation rates from next-generation sequencing data. Translation involves molecules and chemical reactions, hence bioinformatics methods consistent with the laws of chemistry and physics are...

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Detalles Bibliográficos
Autores principales: Sharma, Ajeet K., Sormanni, Pietro, Ahmed, Nabeel, Ciryam, Prajwal, Friedrich, Ulrike A., Kramer, Günter, O’Brien, Edward P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559674/
https://www.ncbi.nlm.nih.gov/pubmed/31120880
http://dx.doi.org/10.1371/journal.pcbi.1007070

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