Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma

Reactive astrocytes evolve after brain injury, inflammatory and degenerative diseases, whereby they undergo transcriptomic re-programming. In malignant brain tumors, their function and crosstalk to other components of the environment is poorly understood. Here we report a distinct transcriptional ph...

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Detalles Bibliográficos
Autores principales: Henrik Heiland, Dieter, Ravi, Vidhya M., Behringer, Simon P., Frenking, Jan Hendrik, Wurm, Julian, Joseph, Kevin, Garrelfs, Nicklas W. C., Strähle, Jakob, Heynckes, Sabrina, Grauvogel, Jürgen, Franco, Pamela, Mader, Irina, Schneider, Matthias, Potthoff, Anna-Laura, Delev, Daniel, Hofmann, Ulrich G., Fung, Christian, Beck, Jürgen, Sankowski, Roman, Prinz, Marco, Schnell, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559986/
https://www.ncbi.nlm.nih.gov/pubmed/31186414
http://dx.doi.org/10.1038/s41467-019-10493-6

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