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Analysis of the artificial vaginal microecology in patients after laparoscopic peritoneal vaginoplasty

To investigate the artificial vaginal microecological features in patients who underwent laparoscopic peritoneal vaginoplasty. 54 cases of patients with artificial vagina after laparoscopic peritoneal vaginoplasty were included in this study. Microecosystem evaluation was performed. Artificial vagin...

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Autores principales: Qin, Chenglu, Luo, Guangnan, Luo, Xin, Lifschutz, Brian N., Zhu, Ziwen, Fang, Yujiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560037/
https://www.ncbi.nlm.nih.gov/pubmed/31186444
http://dx.doi.org/10.1038/s41598-019-44511-w
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author Qin, Chenglu
Luo, Guangnan
Luo, Xin
Lifschutz, Brian N.
Zhu, Ziwen
Fang, Yujiang
author_facet Qin, Chenglu
Luo, Guangnan
Luo, Xin
Lifschutz, Brian N.
Zhu, Ziwen
Fang, Yujiang
author_sort Qin, Chenglu
collection PubMed
description To investigate the artificial vaginal microecological features in patients who underwent laparoscopic peritoneal vaginoplasty. 54 cases of patients with artificial vagina after laparoscopic peritoneal vaginoplasty were included in this study. Microecosystem evaluation was performed. Artificial vaginal functional tests and biopsy from vaginal walls were performed. After laparoscopic peritoneal vaginoplasty, the artificial vaginal flora intensity was level II∼III (88.9%); the vaginal flora diversity was level II∼III (72.2%); the predominant vaginal bacteria were gram-positive macrobacillus (27.8%); approximately 57.4% of the patients had vaginal pH ≤ 4.5; there was no pathogenic bateria or other pathogens; dysbiosis accounted for 53.7% of the patients (64.5% of the patients who had the vaginoplasty operation less than 2 years ago exhibited dysbiosis; 39.1% of the patients who had the operation at least 2 years ago exhibited dysbiosis). Vaginal dysbiosis is common after laparoscopic peritoneal vaginoplasty. However, as time goes by, the artificial vaginal microecological condition gradually becomes normal. Evaluation of vaginal microenvironment after laparoscopic peritoneal vaginoplasty might play an important role in reproductive tract infection prevention and neovagina health care.
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spelling pubmed-65600372019-06-19 Analysis of the artificial vaginal microecology in patients after laparoscopic peritoneal vaginoplasty Qin, Chenglu Luo, Guangnan Luo, Xin Lifschutz, Brian N. Zhu, Ziwen Fang, Yujiang Sci Rep Article To investigate the artificial vaginal microecological features in patients who underwent laparoscopic peritoneal vaginoplasty. 54 cases of patients with artificial vagina after laparoscopic peritoneal vaginoplasty were included in this study. Microecosystem evaluation was performed. Artificial vaginal functional tests and biopsy from vaginal walls were performed. After laparoscopic peritoneal vaginoplasty, the artificial vaginal flora intensity was level II∼III (88.9%); the vaginal flora diversity was level II∼III (72.2%); the predominant vaginal bacteria were gram-positive macrobacillus (27.8%); approximately 57.4% of the patients had vaginal pH ≤ 4.5; there was no pathogenic bateria or other pathogens; dysbiosis accounted for 53.7% of the patients (64.5% of the patients who had the vaginoplasty operation less than 2 years ago exhibited dysbiosis; 39.1% of the patients who had the operation at least 2 years ago exhibited dysbiosis). Vaginal dysbiosis is common after laparoscopic peritoneal vaginoplasty. However, as time goes by, the artificial vaginal microecological condition gradually becomes normal. Evaluation of vaginal microenvironment after laparoscopic peritoneal vaginoplasty might play an important role in reproductive tract infection prevention and neovagina health care. Nature Publishing Group UK 2019-06-11 /pmc/articles/PMC6560037/ /pubmed/31186444 http://dx.doi.org/10.1038/s41598-019-44511-w Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Qin, Chenglu
Luo, Guangnan
Luo, Xin
Lifschutz, Brian N.
Zhu, Ziwen
Fang, Yujiang
Analysis of the artificial vaginal microecology in patients after laparoscopic peritoneal vaginoplasty
title Analysis of the artificial vaginal microecology in patients after laparoscopic peritoneal vaginoplasty
title_full Analysis of the artificial vaginal microecology in patients after laparoscopic peritoneal vaginoplasty
title_fullStr Analysis of the artificial vaginal microecology in patients after laparoscopic peritoneal vaginoplasty
title_full_unstemmed Analysis of the artificial vaginal microecology in patients after laparoscopic peritoneal vaginoplasty
title_short Analysis of the artificial vaginal microecology in patients after laparoscopic peritoneal vaginoplasty
title_sort analysis of the artificial vaginal microecology in patients after laparoscopic peritoneal vaginoplasty
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560037/
https://www.ncbi.nlm.nih.gov/pubmed/31186444
http://dx.doi.org/10.1038/s41598-019-44511-w
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