Non-neutral evolution of H3.3-encoding genes occurs without alterations in protein sequence

Histone H3.3 is a developmentally essential variant encoded by two independent genes in human (H3F3A and H3F3B). While this two-gene arrangement is evolutionarily conserved, its origins and function remain unknown. Phylogenetics, synteny and gene structure analyses of H3.3 genes from 32 metazoan gen...

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Detalles Bibliográficos
Autores principales: Muhire, Brejnev M., Booker, Matthew A., Tolstorukov, Michael Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560044/
https://www.ncbi.nlm.nih.gov/pubmed/31186448
http://dx.doi.org/10.1038/s41598-019-44800-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560044/
https://www.ncbi.nlm.nih.gov/pubmed/31186448
http://dx.doi.org/10.1038/s41598-019-44800-4

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