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MIR17HG-miR-18a/19a axis, regulated by interferon regulatory factor-1, promotes gastric cancer metastasis via Wnt/β-catenin signalling

MIR17HG, located on chromosome 13, is a class of Pri-miRNAs that generates six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1. These miRNAs are ubiquitously overexpressed in diverse tumour types and exhibit complex biological links to tumour metastasis. We demonstrated that MIR17H...

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Detalles Bibliográficos
Autores principales: Yuan, Jingsheng, Tan, Lulu, Yin, Zhijie, Zhu, Wenzhong, Tao, Kaixiong, Wang, Guobing, Shi, Wenjia, Gao, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560107/
https://www.ncbi.nlm.nih.gov/pubmed/31186404
http://dx.doi.org/10.1038/s41419-019-1685-z

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