Bone Marrow Transplantation 1957-2019

Clinical bone marrow transplantation started in 1957 at a time when remarkably little was known about hematopoietic stems cells, immune responses to transplants or the identity of transplant antigens. This review will delineate the substantial increase in knowledge about these three areas gained bet...

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Detalles Bibliográficos
Autores principales: Simpson, Elizabeth, Dazzi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560153/
https://www.ncbi.nlm.nih.gov/pubmed/31231381
http://dx.doi.org/10.3389/fimmu.2019.01246
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author Simpson, Elizabeth
Dazzi, Francesco
author_facet Simpson, Elizabeth
Dazzi, Francesco
author_sort Simpson, Elizabeth
collection PubMed
description Clinical bone marrow transplantation started in 1957 at a time when remarkably little was known about hematopoietic stems cells, immune responses to transplants or the identity of transplant antigens. This review will delineate the substantial increase in knowledge about these three areas gained between then and 1992 when the Ceppellini School course on Bone Marrow Transplantation was held, along with the progress made in clinical application, as well as the stumbling blocks that remained to be overcome by further research to advance knowledge. It will outline the significant progress made between 1992 and the present year, 2019, and the remaining problems.
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spelling pubmed-65601532019-06-21 Bone Marrow Transplantation 1957-2019 Simpson, Elizabeth Dazzi, Francesco Front Immunol Immunology Clinical bone marrow transplantation started in 1957 at a time when remarkably little was known about hematopoietic stems cells, immune responses to transplants or the identity of transplant antigens. This review will delineate the substantial increase in knowledge about these three areas gained between then and 1992 when the Ceppellini School course on Bone Marrow Transplantation was held, along with the progress made in clinical application, as well as the stumbling blocks that remained to be overcome by further research to advance knowledge. It will outline the significant progress made between 1992 and the present year, 2019, and the remaining problems. Frontiers Media S.A. 2019-06-05 /pmc/articles/PMC6560153/ /pubmed/31231381 http://dx.doi.org/10.3389/fimmu.2019.01246 Text en Copyright © 2019 Simpson and Dazzi. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Simpson, Elizabeth
Dazzi, Francesco
Bone Marrow Transplantation 1957-2019
title Bone Marrow Transplantation 1957-2019
title_full Bone Marrow Transplantation 1957-2019
title_fullStr Bone Marrow Transplantation 1957-2019
title_full_unstemmed Bone Marrow Transplantation 1957-2019
title_short Bone Marrow Transplantation 1957-2019
title_sort bone marrow transplantation 1957-2019
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560153/
https://www.ncbi.nlm.nih.gov/pubmed/31231381
http://dx.doi.org/10.3389/fimmu.2019.01246
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