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Ganglioside GQ1b ameliorates cognitive impairments in an Alzheimer’s disease mouse model, and causes reduction of amyloid precursor protein

Brain-derived neurotrophic factor (BDNF) plays crucial roles in memory impairments including Alzheimer’s disease (AD). Previous studies have reported that tetrasialoganglioside GQ1b is involved in long-term potentiation and cognitive functions as well as BDNF expression. However, in vitro and in viv...

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Detalles Bibliográficos
Autores principales:	Shin, Min-Kyoo, Choi, Min-Suk, Chae, Hyang-Ji, Kim, Ji-Won, Kim, Hong-Gi, Kim, Kil-Lyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560179/ https://www.ncbi.nlm.nih.gov/pubmed/31186474 http://dx.doi.org/10.1038/s41598-019-44739-6

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