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Gephyrin suppresses lung squamous cell carcinoma development by reducing mTOR pathway activation
Background: The mTOR pathway is altered in a multitude of cancers, including lung cancer; however, abnormal activation in this pathway is less common in lung adenocarcinoma (LUAD) than in lung squamous cell carcinoma (LUSC). Gephyrin is a highly conserved and widely expressed ancient protein in vert...
Autores principales: | Zhang, Xiang, Cheng, Dezhi, Liu, Yu, Wu, Yuanbo, He, Zhifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560210/ https://www.ncbi.nlm.nih.gov/pubmed/31239782 http://dx.doi.org/10.2147/CMAR.S204358 |
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