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A new frontier of image guidance: Organs at risk avoidance with MRI‐guided respiratory‐gated intensity modulated radiotherapy: Technical note and report of a case

The case of a 50‐year‐old man affected by a rhabdomiosarcoma metastatic lesion in the left flank Is reported. The patient was addressed to 50.4 Gy radiotherapy with concomitant chemotherapy in order to locally control the lesion. A Tri‐60‐Co magnetic resonance hybrid radiotherapy unit was used for t...

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Autores principales: Massaccesi, Mariangela, Cusumano, Davide, Boldrini, Luca, Dinapoli, Nicola, Fionda, Bruno, Teodoli, Stefania, Azario, Luigi, Mattiucci, Gian Carlo, Balducci, Mario, Cellini, Francesco, Valentini, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560311/
https://www.ncbi.nlm.nih.gov/pubmed/31055870
http://dx.doi.org/10.1002/acm2.12575
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author Massaccesi, Mariangela
Cusumano, Davide
Boldrini, Luca
Dinapoli, Nicola
Fionda, Bruno
Teodoli, Stefania
Azario, Luigi
Mattiucci, Gian Carlo
Balducci, Mario
Cellini, Francesco
Valentini, Vincenzo
author_facet Massaccesi, Mariangela
Cusumano, Davide
Boldrini, Luca
Dinapoli, Nicola
Fionda, Bruno
Teodoli, Stefania
Azario, Luigi
Mattiucci, Gian Carlo
Balducci, Mario
Cellini, Francesco
Valentini, Vincenzo
author_sort Massaccesi, Mariangela
collection PubMed
description The case of a 50‐year‐old man affected by a rhabdomiosarcoma metastatic lesion in the left flank Is reported. The patient was addressed to 50.4 Gy radiotherapy with concomitant chemotherapy in order to locally control the lesion. A Tri‐60‐Co magnetic resonance hybrid radiotherapy unit was used for treatment delivery and a respiratory gating protocol was applied for the different breathing phases (Free Breathing, Deep Inspiration Breath Hold and Final Expiration Breath Hold). Three intensity modulated radiation therapy (IMRT) plans were calculated and Final Expiration Breath Hold plan was finally selected due to the absence of PTV coverage differences and better organs at risk sparing (i.e. kidneys). This case report suggests that organs at risk avoidance with MRI‐guided respiratory‐gated Radiotherapy is feasible and particularly advantageous whenever sparing the organs at risk is of utmost dosimetric or clinical importance.
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spelling pubmed-65603112019-06-17 A new frontier of image guidance: Organs at risk avoidance with MRI‐guided respiratory‐gated intensity modulated radiotherapy: Technical note and report of a case Massaccesi, Mariangela Cusumano, Davide Boldrini, Luca Dinapoli, Nicola Fionda, Bruno Teodoli, Stefania Azario, Luigi Mattiucci, Gian Carlo Balducci, Mario Cellini, Francesco Valentini, Vincenzo J Appl Clin Med Phys Technical Notes The case of a 50‐year‐old man affected by a rhabdomiosarcoma metastatic lesion in the left flank Is reported. The patient was addressed to 50.4 Gy radiotherapy with concomitant chemotherapy in order to locally control the lesion. A Tri‐60‐Co magnetic resonance hybrid radiotherapy unit was used for treatment delivery and a respiratory gating protocol was applied for the different breathing phases (Free Breathing, Deep Inspiration Breath Hold and Final Expiration Breath Hold). Three intensity modulated radiation therapy (IMRT) plans were calculated and Final Expiration Breath Hold plan was finally selected due to the absence of PTV coverage differences and better organs at risk sparing (i.e. kidneys). This case report suggests that organs at risk avoidance with MRI‐guided respiratory‐gated Radiotherapy is feasible and particularly advantageous whenever sparing the organs at risk is of utmost dosimetric or clinical importance. John Wiley and Sons Inc. 2019-05-04 /pmc/articles/PMC6560311/ /pubmed/31055870 http://dx.doi.org/10.1002/acm2.12575 Text en © 2019 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Technical Notes
Massaccesi, Mariangela
Cusumano, Davide
Boldrini, Luca
Dinapoli, Nicola
Fionda, Bruno
Teodoli, Stefania
Azario, Luigi
Mattiucci, Gian Carlo
Balducci, Mario
Cellini, Francesco
Valentini, Vincenzo
A new frontier of image guidance: Organs at risk avoidance with MRI‐guided respiratory‐gated intensity modulated radiotherapy: Technical note and report of a case
title A new frontier of image guidance: Organs at risk avoidance with MRI‐guided respiratory‐gated intensity modulated radiotherapy: Technical note and report of a case
title_full A new frontier of image guidance: Organs at risk avoidance with MRI‐guided respiratory‐gated intensity modulated radiotherapy: Technical note and report of a case
title_fullStr A new frontier of image guidance: Organs at risk avoidance with MRI‐guided respiratory‐gated intensity modulated radiotherapy: Technical note and report of a case
title_full_unstemmed A new frontier of image guidance: Organs at risk avoidance with MRI‐guided respiratory‐gated intensity modulated radiotherapy: Technical note and report of a case
title_short A new frontier of image guidance: Organs at risk avoidance with MRI‐guided respiratory‐gated intensity modulated radiotherapy: Technical note and report of a case
title_sort new frontier of image guidance: organs at risk avoidance with mri‐guided respiratory‐gated intensity modulated radiotherapy: technical note and report of a case
topic Technical Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560311/
https://www.ncbi.nlm.nih.gov/pubmed/31055870
http://dx.doi.org/10.1002/acm2.12575
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